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Repeatability of hyperpolarized 129-Xe and oxygen-enhanced MRI

Repeatability and correlation of hyperpolarized xenon-129 and oxygen-enhanced MRI parameters in healthy volunteers

by Paul J.C. Hughes, Marta Tibiletti, Matthew J. Heaton, Ho-Fung Chan, Guilhem J. Collier, Matthew Austin, Laurie J. Smith, Jim Lithgow, Josephine H. Naish, Jim M. Wild, and Geoff J.M. Parker on behalf of the TRISTAN Consortium


ISMRM 2020

 

Abstract #2305

Hyperpolarised xenon-129 MRI has shown utility in longitudinal assessment of lung structure and function, and has been shown to be a repeatable method. Oxygen enhanced MRI is a cheaper method of imaging different aspects of lung function. This work aimed to assess a single-centre repeatability of multiple metrics from both imaging methods in volunteers, and assess any correlations between xenon-129 and oxygen enhanced metrics of lung function.